Resveratrol and Alcoholism

Effects of Resveratrol on Liver, Liver Fats, and Liver Disease

Resveratrol Alcoholism
Resveratrol & Alcoholism

Alcoholism has one mainstay side effect – fatty liver buildup.

It seems strange to suggest that Resveratrol, one of the main ingredients in red wine, can actually help to protect the liver against fatty buildup and potentially treat the fat already accumulated in the liver.

Studies performed at the University of South Florida Sciences Center in Tampa have been conducted to study the effects of Resveratrol on mice whose livers have been fattened to a state comparable to that of a lifelong alcoholic’s using ethanol feed.

Those studies are encouraging for people affected with fatty liver disease, whether caused by alcohol consumption, or even for the genetically predisposed. Read on to find out why.

Adiponectin and Peroxiso-what?

Whereas chronic alcohol abuse is shown to markedly hinder the activation of fat metabolizing molecules in the liver, Resveratrol is shown in studies to activate these molecules and help to stabilize the liver. Two important factors in liver health are Peroxisomes and Adiponectin.

Peroxisomes are organelles containing vital enzymes that participate in the metabolism of fatty acids and many other metabolites. Resveratrol is shown to suppress binding proteins in the alcohol and activate the Peroxisome receptors/co-activators in the liver

Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism. Treating alcoholic mice livers with Resveratrol dramatically increased the flow of Adiponectin in very little time.

Study Results

Upon administering Resveratrol to the test group of mice, scientists discovered that not only did the fat in the Resveratrol-treated mice livers break down quicker and process faster than the control group, the ‘alcoholic’ mice who were given Resveratrol regularly actually had less fat overall in their livers than the control group of alcoholic mice.

Resveratrol Liver Disease
Resveratrol and Liver Disease

Prolonged Resveratrol treatment led to reduced lipid synthesis, faster fatty acid oxidation and even completely prevented liver steatosis (the accumulation of fats in the liver, also called Fatty Liver Disease) for all of the test group mice.

In Conclusion

Scientists believe that their findings suggest that Resveratrol can be effective in protecting and treating the liver in mice against all of the effects of alcohol abuse.

It is hard to predict what will happen in the future, but the studies do demonstrate that there are potential benefits to using Resveratrol to prevent or treat damage and disease in human livers caused by a lifetime of alcohol abuse.

If you are an alcoholic or even a regular drinker, you could clearly benefit from supplementing with Resveratrol on a daily basis. I used to drink regularly with my girlfriends back in college, but now I’m relying on Resveratrol to help me repair the damage I did back then.

Drinking more wine however, is probably not the answer. An alcohol-free Resveratrol supplement is probably your best bet. Click here to get a free 14 day trial of RezEx.


AJP – Gastrointestinal and Liver Physiology – online archives, Oct. 2008 issue; “Resveratrol alleviates alcoholic fatty liver in mice” (abstract); Joanne M. Ajmo, Xiaomei Liang, Christopher Q. Rogers, Brandi Pennock, and Min You

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